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Proper endothelial function is an important factor for optimal heart health. Even with cholesterol and blood sugar levels in the healthy range, aging individuals need to maintain youthful integrity of their endothelium, the thin inner layer of our circulatory system.
CORDIART™, an extract from sweet orange peels, activates endothelial production of the bodily messenger nitric oxide, which signals the smooth muscles of the blood vessels to relax, inducing vasodilation to support healthy circulation. In a clinical trial, supplementation with 500 mg of CORDIART daily produced an 18% improvement in flow mediated dilation, a marker of endothelial function. In addition, CORDIART™ inhibited the pro-inflammatory factors C-reactive protein and serum amyloid A that disrupt healthy nitric oxide production.