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Biotin is a member of the water-soluble B-complex family, normally only required in minute amounts. Biotin is used as a cofactor of enzymes involved in fatty acid metabolism, gluconeogenesis, and amino acid catabolism, and is essential in maintaining internal balance.
Biotin plays an important role in metabolic functioning as a coenzyme carrier of activated carbon dioxide in the TCA cycle (also known as the Krebs cycle). In its coenzyme form, biotin synthesises glucose from non-carbohydrate sources, and synthesises and breaks down certain fatty acids and amino acids.