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Super Ubiquinol CoQ10 with BioPQQ® is one of Life Extension´s latest developments in its mitochondria-boosting range. Super Ubiquinol CoQ10 with BioPQQ® contains shilajit (which studies have shown to double CoQ10 levels in the mitochondria) and PQQ, which not only protects mitochondria from oxidative stress, but also promotes the spontaneous generation of new mitochondria within aging cells, a process known as mitochondrial biogenesis. Super Ubiquinol CoQ10 with BioPQQ® ´s three active ingredients each provide enhanced mitochondrial support.
CoQ10 is needed to convert the energy from fats and sugars into usable cellular energy. However, as we age, the body´s production of CoQ10 decreases considerably. Statins - a class of drugs used to lower cholesterol levels - also reduce CoQ10 levels in the blood, and possibly also in the tissues. Statins have been shown to reduce plasma CoQ10 levels by almost 40%. Yet the normal aging process reduces CoQ10 levels in the heart muscle wall by 72%. Consequently, extremely low levels of CoQ10 can occur, causing a severe depletion of cellular energy.
Studies have shown that the ubiquinol form of CoQ10 has 8 times the absorbability of ubiquinone and that higher levels of ubiquinol remain in the blood much longer than ubiquinone. In trials with middle-aged mice, ubiquinol was shown to be 40% more effective than ubiquinone in slowing age-related changes. Super Ubiquinol CoQ10 with BioPQQ® provides the highly bioavailable ubiquinol form of patented CoQ10 in an advanced delivery system delivering unparalleled absorption.
Recent studies have revealed that when shilajit is combined with CoQ10, there is a dramatic increase in cellular energy levels. PrimaVie® shilajit has been shown to double CoQ10 levels in mitochondria. Combining CoQ10 with shilajit produced a 56% increase in cerebral energy production – 40% better than when CoQ10 was administered alone, while in muscle there was a 144% increase in energy production – 27% better than CoQ10 alone. Shilajit is also a rich source of essential substances that help the mitochondria convert fats and sugars into ATP (adenosine triphosphate), the body´s most important source of energy which is involved in a large number of cellular functions.
Until recently, the only ways for aging individuals to encourage mitochondrial biogenesis (an increase in declining numbers of mitochondria) were long-term calorie restriction or physical activity to the point of exhaustion, both of which are difficult or impractical for most people to implement. Now, with PQQ there is a viable alternative: PQQ (pyrroloquinoline quinone) has been shown to promote spontaneous production of new mitochondria. PQQ promotes youthful cellular function in three different ways:
PQQ activates genes that stimulate the generation of new mitochondria and interacts beneficially with genes directly involved in mitochondrial health. These genes also support healthy body weight, normal fat and sugar metabolism and youthful mitosis (cell division).
Mitochondria have their own DNA which is distinct from the DNA in the cell nucleus. However mitochondrial DNA is relatively unprotected compared to nuclear DNA. Like CoQ10, PQQ is a potent antioxidant. Its powerful antioxidant properties and favorable gene-expression profile both make a very considerable contribution to mitochondrial protection.
PQQ´s exceptional molecular stability allows it to facilitate thousands of biochemical reactions in the mitochondria without breaking down, thus providing maximum antioxidant and bioenergetic support.
PQQ is an essential nutrient, which means that it is a nutrient required for normal human body function that either cannot be synthesized by the body at all, or cannot be synthesized in amounts adequate for good health and thus must be obtained from a dietary source. There is a large amount of research showing that - both alone and particularly in combination with CoQ10 – it supports cardiac health and brain function.
The ideal dose is 20 mg or 2 softgels a day.
Super Ubiquinol CoQ10 with BioPQQ® can be ordered online. Prompt delivery assured.