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Life Extension Optimized Folate (L-Methylfolate)


Home / Optimized Folate (L-Methylfolate) (100070)

WE’RE ON HOLIDAY - Orders will go out again from Monday August 14th - HAPPY HOLIDAYS!


€35,50 Incl. tax
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Delivery time 2 - 5 days

Article number: 100070
Delivery time: 2 - 5 days


Folic acid or folate (L-Methylfolate) is a B vitamin that is involved in neurotransmitter synthesis and a large number of important enzymatic reactions throughout the body. By reducing homocysteine levels - high levels of homocysteine have been associated with a number of conditions including increased risk of cardiovascular disease, stroke, macular degeneration and dementia – it makes a valuable contribution to cardiovascular health and nervous system function. Yet many people have a genetic inability to convert folic acid to its biologically active 5-methyltetrahydrofolate (5-MTHF) form, leaving them with lower than optimal folic acid serum levels and elevated homocysteine levels, also known as folic acid or folate deficiency. Such individuals would benefit from taking bioactive 5-MTHF supplements (a type of folic acid supplements) directly in its bioavailable form. This has been declassified as a drug and is now available as a vitamin supplement or folic acid supplement.

Recent research has shown that the administration of bioactive 5-MTHF to patients with coronary artery disease resulted in a 700% higher plasma folate concentration compared with standard folic acid supplements alone. This difference was irrespective of the patient’s genotype.

Elevated homocysteine levels carry with them a greater risk of cognitive decline. Unlike folic acid, 5-MTHF is able to cross the blood-brain barrier and enhance the synthesis of a Acetylcholine, the neurotransmitter associated with memory, in the brain. Research has also shown that supplementing with methylocobalamin (the active form of vitamin B12 supplements), vitamin B6 and riboflavin can enhance the effectiveness of 5-MTHF.

Optimised Folic Acid (L-Methylfolate) can be ordered online. Prompt delivery assured.


Jonas 13-06-2016 11:47

Bijzonder middeltje, Ik gebruik optimized, tijdens een periode van intellectuele overspannenheid of examens. Werkt heel goed. mijn geheugen en concentratie varen er wel bij, studeren gaat makkelijker en ik kan de leerstof sneller en beter onthouden. Ik merk ook dat ik ook minder vlug moe wordt en dat kan ik gebruiken tijdens de examens. Top product. Prima webshop. Vlotte levering.

Wim C. 26-02-2016 07:21

Moeder kan niet goed meer onthouden zeker de pasgebeurde feiten zijn voor haar moeilijk. Op aanraden van een vriend ( die reeds geruime tijd al een tevreden klant is bij apran.com), heeft mijn moeder optimized folate I metthylfolate, beginnen innemen en ja na toch al ongeveer twaalf weken merk ik een goed verbetering op, doet deugd mijn moeder terug wat alerter te zien.

5 stars based on 2 reviews